The scope of wildfires over the previous decade has brought these natural hazards to the forefront of risk management. Wildfires threaten human health, safety, and property, and there is a need for comprehensive and readily usable wildfire simulation platforms that can be applied effectively by wildfire experts to help preserve physical infrastructure, biodiversity, and landscape integrity. Evaluating such platforms is important, particularly in determining the platforms’ reliability in forecasting the spatiotemporal trajectories of wildfire events. This study evaluated the predictive performance of a wildfire simulation platform that implements a Monte Carlo-based wildfire model called WyoFire. WyoFire was used to predict the growth of 10 wildfires that occurred in Wyoming, USA, in 2017 and 2019. The predictive quality of this model was determined by comparing disagreement and agreement areas between the observed and simulated wildfire boundaries. Overestimation–underestimation was greatest in grassland fires (>32) and lowest in mixed-forest, woodland, and shrub-steppe fires (<−2.5). Spatial and statistical analyses of observed and predicted fire perimeters were conducted to measure the accuracy of the predicated outputs. The results indicate that simulations of wildfires that occurred in shrubland- and grassland-dominated environments had the tendency to over-predict, while simulations of fires that took place within forested and woodland-dominated environments displayed the tendency to under-predict.