Eleven cases of suspected driving under the influence (DUI) of flualprazolam are presented. Data from police reports and drug recognition examinations (DRE), when available, were evaluated. In all cases, significant driving impairments were observed including weaving, driving slowly, stopping in the roadway, or collisions. Objective signs of impairment in all cases were generally consistent with those expected from central nervous system depressants. Both the mean and median blood flualprazolam concentrations were less than 15 ng/mL. Though comprehensive analysis was not performed on each specimen, the data from this study support the conclusion that flualprazolam at low concentrations may significantly impair the ability to safely drive.

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