No abstract

A second example of anti-Pra was recognized in a newborn infant which exhibited several signs of development disease. The antibody was complement-fixing 19S IgM and showed a high thermal range but no detectable haemolytic anaemia was associated. It gave negative reactions with a panel of animal cells as well as with two samples of human En(a-) cells. The latter, however, could absorb the antibody.

No abstract

A new, rare antigen, FAR, was discovered in connection with a hemolytic disease of the newborn. This very rare antigen was not encountered in 14,273 Caucasians tested. It is probably linked to the MNSs system (p<0.004). The anti-FAR antibody, which is of immune origin, is also very rare: it has been sought unsuccessfully in 541 sera. The identification of this antigen provides further evidence of a comparatively high mutation rate in some sites on the MNSs locus and of its practical interest in both pathology and human genetic studies.