New advances in preparation of homoallylamines are discussed. Novel syntheses of saturated nitrogencontaining heterocycles from N-substituted homoallylic amines are reviewed.

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New derivatives of 4-N-benzylamino-4-hetarylbut-1-ene containing a pyridyl nucleus were synthesized from benzylamines and pyridine aldehydes. N-oxide derivatives were obtained from these homoallylamines. Study of the antiparasitic properties of obtained pyridine derivatives as well as of four related benzazepines previously described, was carried out using cytotoxicity assays against Trichomonas vaginalis and epimastigote form of Trypanosoma cruzi protozoa. Compounds showing activity against epimastigote T. cruzi were tested against the amastigote form; unspecific cytotoxicity against macrophages was also studied.

In this contribution, we report on the electronic energy transfer dynamics of bichromophoric systems incorporating two pyrene chromophores tethered by variable-length flexible alkyloxy chains to p-phenylenevinylene oligomers. These were studied using UV-vis absorption and both steady state and time-resolved fluorescence spectroscopy. Time-resolved emission measurements showed an efficient photoinduced energy transfer process in all the multichromophoric systems, which occurs on the time scale of tens of picoseconds after excitation at 265 nm. The energy transfer process is especially efficient in systems where the linker is formed by eight atoms (up to k(ET) ≈ 2.7 × 10(10) s(-1)), which, despite not being the shortest bridge studied, allows the approach of the donor and acceptor chromophores due to an appropriate number of flexible single bonds. Using Förster theory, we calculated the donor-acceptor distance in each triad from the experimental energy transfer rate, finding them to be in the range 8.8-10 Å.