IntroductionStroke survivors usually experience long-lasting functional, emotional and social consequences that might contribute to sedentary behaviour and participation restrictions, which are important targets to address during rehabilitation. However, the trajectory and inter-relationship between these factors are unknown.Methods and analysisPart&Sed is a research project based on an observational study design with 6 and 12 months of follow-ups in stroke survivors. In addition, a qualitative analysis of the impact of the stroke on the stroke survivor, validation of the Satisfaction with Daily Occupation-Occupational Balance assessment tool and analysis of the reliability of the Fitbit Inspire 2 activity tracker wristband will be carried out. Participants will be chronic stroke survivors with independent walking capacity. Sociodemographic and clinical data, physical activity, ambulation, sleep, quality of life, anxiety and depression, community participation, and occupational satisfaction and balance, as well as data provided by the activity tracker wristband, will be collected. In addition, if the participant has a primary caregiver, the caregiver will also be monitored. A minimum of 130 participants will be recruited to conduct a random-effects multiple regression model. Mixed models for repeated measures will assess the variation over time of the different variables associated with participation and sedentary behaviour. Psychometric properties (eg, internal consistency, construct validity, test–retest reliability) of the Satisfaction with Daily Occupation-Occupational Balance will be determined. Additionally, intraclass correlation coefficients and minimum detectable change will be calculated to assess intrasubject reliability of physical activity and sleep parameters recorded by the Fitbit Inspire 2. The qualitative analysis process will be carried out using the analysis proposed by Giorgi.Ethics and disseminationThe study received ethical approval from the Spanish Regional Ethics Committee ‘Comité de Ética de la Investigación de la Comunidad de Aragón’ (PI21/333). The results will be made available via peer-reviewed publications, international conferences and official channels.

Background: Stroke survivors undertake low levels of physical activity and participation in daily life activities, but there are no reviews on the relationship between physical activity and participation. This systematic review and meta-analyses-based data synthesis will aim to cross-sectionally and longitudinally describe and estimate the relationship between participation in daily life activities and physical activity in stroke survivors. Methods and analysis: This protocol follows the Preferred Reporting Items for Systematic Review and Meta-Analysis Protocols (PRISMA-P). Six databases (PudMed, Web of Science, Scopus, PEDro, SPORTDiscus, and Rehabilitation & Sport Medicine Source) will be searched using terms grouped into three categories: stroke, physical activity, and participation in daily life activities. Observational and experimental studies assessing participation and physical activity levels in adult stroke survivors in English or Spanish will be included. The methodological quality of the studies will be assessed independently by 2 investigators, with the Newcastle-Ottawa scale. Study and sample characteristics, and physical activity and participation outcome data will be extracted. Additionally, if available, repeated measures and correlation values between physical activity and participation outcomes will be extracted. The Hedges-Olkin method will be used for pooling correlation values and a random-effects meta-analysis following restricted maximum likelihood estimation for pooling effect sizes of those studies prospectively assessing the same measures of participation and physical activity. Subgroup analyses will be performed if a sufficient number of studies are found. Heterogeneity between studies results will be analyzed using I2 statistics, and publication bias will be examined using funnel plots and Egger's tests. Discussion: This will be the first systematic review with meta-analysis-based data synthesis to provide information on the relationship between physical activity and participation in stroke survivors. Findings are likely to inform, the design of health prevention protocols and the development of healthy behavior change interventions.