The beauty of the proportional-integral-derivative (PID) algorithm for feedback control is its simplicity and efficiency. Those are the main reasons why PID controller is the most common form of feedback. PID combines the three natural ways of taking into account the error: the actual (proportional), the accumulated (integral), and the predicted (derivative) values; the three gains depend on the magnitude of the error, the time required to eliminate the accumulated error, and the prediction horizon of the error. This paper explores the new meaning of integral and derivative actions, and gains, derived by the consideration of non-integer integration and differentiation orders, i.e., for fractional order PID controllers. The integral term responds with selective memory to the error because of its non-integer order λ , and corresponds to the area of the projection of the error curve onto a plane (it is not the classical area under the error curve). Moreover, for a fractional proportional-integral (PI) controller scheme with automatic reset, both the velocity and the shape of reset can be modified with λ . For its part, the derivative action refers to the predicted future values of the error, but based on different prediction horizons (actually, linear and non-linear extrapolations) depending on the value of the differentiation order, μ . Likewise, in case of a proportional-derivative (PD) structure with a noise filter, the value of μ allows different filtering effects on the error signal to be attained. Similarities and differences between classical and fractional PIDs, as well as illustrative control examples, are given for a best understanding of new possibilities of control with the latter. Examples are given for illustration purposes.

No abstract

Cardiovascular diseases (CVDs) remain the leading cause of death worldwide, according to recent reports from the World Health Organization (WHO). This fact encourages research into the cardiovascular system (CVS) from multiple and different points of view than those given by the medical perspective, highlighting among them the computational and mathematical models that involve experiments much simpler and less expensive to be performed in comparison with in vivo or in vitro heart experiments. However, the CVS is a complex system that needs multidisciplinary knowledge to describe its dynamic models, which help to predict cardiovascular events in patients with heart failure, myocardial or valvular heart disease, so it remains an active area of research. Firstly, this paper presents a novel electrical model of the CVS that extends the classic Windkessel models to the left common carotid artery motivated by the need to have a more complete model from a medical point of view for validation purposes, as well as to describe other cardiovascular phenomena in this area, such as atherosclerosis, one of the main risk factors for CVDs. The model is validated by clinical indices and experimental data obtained from clinical trials performed on a pig. Secondly, as a first step, the goodness of a fractional-order behavior of this model is discussed to characterize different heart diseases through pressure–volume (PV) loops. Unlike other models, it allows us to modify not only the topology, parameters or number of model elements, but also the dynamic by tuning a single parameter, the characteristic differentiation order; consequently, it is expected to provide a valuable insight into this complex system and to support the development of clinical decision systems for CVDs.

No abstract

No abstract