The aim of this study is three fold: (1) to investigate the pulsatile blood flow in the brachial artery and its ulnar and radial tributaries in the attempt to understand aspects related to blood pressure measurements (BPM); (2) to assess the flow vessel-muscle structural interactions that may occur normally and under occlusive constraints (the radial artery); (3) to investigate the BPM information for different rheological models of blood. Mathematical modeling and numerical simulations are used to solve these objectives.
Magnetic drug targeting (MDT) therapy is usually controlled through the magnetic field produced by a permanent magnet; the solution proposed and assessed here considers a planar spiral coil (PSC) or a system of such coils, as an equally effective magnetic field source. The PSC may be designed to provide proper configurations of the magnetic field gradients, required for the generation of high magnetic body forces and to limit, in the same time, unwanted side effects affecting adjacent tissue (heating, excitable tissue stimulation). Simplified numerical models (2D projections) and more realistic structures (3D representations) are shown and analyzed in the paper; the electromagnetic and heat transfer problems are solved for different powering schemes applied to the coils.
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