Background:To what extent hospital use and medical resources are used on hemophilia care in China's health care system is unknown.Objectives: This study was based on a single center in China and was conducted to comprehensively assess the resource use for hospitalization of people with hemophilia.
Methods:We analyzed clinical characteristics, diagnosis, inhibitor status, reasons, length of stay, and hospital costs of 323 hospitalizations in which hemophilia must be considered as the main factor for hospitalization from January 2009 to December
Inherited factor VII (FVII) deficiency, transmitted with an autosomal recessive pattern, is a rare congenital coagulation disorder with an estimated prevalence of one in 500 000. [1][2][3] Numerous variants and some polymorphisms in the F7 gene, located on chromosome 13q34, are associated with varying degrees of FVII activity (FVII:C). 1 FVII, interacting with tissue factor, plays an important role in the coagulation cascade. Patients with FVII deficiency display a wide range of clinical phenotypes, from the absence of bleeding symptoms to life-or limb-threatening central nervous system (CNS), gastrointestinal (GI) haemorrhages or haemarthrosis.The analyses of patients from several international registries 3-10 have provided data on phenotype, genotype and management of FVII deficiency. A weak association between
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.