The present paper introduces the concept of integral manifolds for a class of delayed impulsive neural networks of Cohen–Grossberg-type with reaction–diffusion terms. We establish new existence and boundedness results for general types of integral manifolds with respect to the system under consideration. Based on the Lyapunov functions technique and Poincarѐ-type inequality some new global stability criteria are also proposed in our research. In addition, we consider the case when the impulsive jumps are not realized at fixed instants. Instead, we investigate a system under variable impulsive perturbations. Finally, examples are given to demonstrate the efficiency and applicability of the obtained results.

The paper proposes an extension of stability analysis methods for a class of impulsive reaction-diffusion Cohen-Grossberg delayed neural networks by addressing a challenge namely stability of sets. Such extended concept is of considerable interest to numerous systems capable of approaching not only one equilibrium state. Results on uniform global asymptotic stability and uniform global exponential stability with respect to sets for the model under consideration are established. The main tools are expansions of the Lyapunov method and the comparison principle. In addition, the obtained results for the uncertain case contributed to the development of the stability theory of uncertain reaction-diffusion Cohen-Grossberg delayed neural networks and their applications. Moreover, examples are given to demonstrate the feasibility of our results.

In this paper we study an impulsive delayed reaction-diffusion model applied in biology. The introduced model generalizes existing reaction-diffusion delayed epidemic models to the impulsive case. The integral manifolds notion has been introduced to the model under consideration. This notion extends the single state notion and has important applications in the study of multi-stable systems. By means of an extension of the Lyapunov method integral manifolds’ existence, results are established. Based on the Lyapunov functions technique combined with a Poincarè-type inequality qualitative criteria related to boundedness, permanence, and stability of the integral manifolds are also presented. The application of the proposed impulsive control model is closely related to a most important problems in the mathematical biology—the problem of optimal control of epidemic models. The considered impulsive effects can be used by epidemiologists as a very effective therapy control strategy. In addition, since the integral manifolds approach is relevant in various contexts, our results can be applied in the qualitative investigations of many problems in the epidemiology of diverse interest.

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