For Abstract see ChemInform Abstract in Full Text.

Reactions catalyzed by oxygenase enzymes (mono or dioxygenases) are interesting for applications in organic synthesis. There are numerous examples of such reactions in biological systems, yet there are few chemical reagents or catalysts that can compete with biocatalysts. Examples of monoxygenases catalyzed biotransformations are shown in Figure 16.1-1. These include heteroatom oxygenation, aromatic hydroxylation, Bayer-Villiger oxidation, double-bond epoxidation and hydroxylation of nonactivated hydrocarbon atoms. The latter can occur with regio-, stereo-,