Two functions namely initial lung deposition and lung retention per unit faecal excretion rate are constructed primarily based on the excretion pattern of four subjects exposed to (239)Pu. In the absence of initial clear knowledge about the class of compound inhaled, faecal to urine excretion ratio was used to infer the type of inhaled class. Trends in the urine and faecal data had suggested that the intake was due to mixed class of plutonium compound for each case. With the assumption of 1:1 mixture of plutonium M&S class inhaled compound, faecal excretion rates for only S-class intake were worked out. Uptake inferred based on their urinary data had suggested it to be of similar level within 40% of uncertainty for 5 microm particle size distribution. Data, all the four cases, were pooled for analysis citing the similar level of intake, particle size distribution, nature and pattern of work. The function obtained was tested for S-class lung retention and faecal excretion rate value. These functions are handy tool for estimating initial lung burden and lung retention value for low level of S-class plutonium intake based on subject faecal analysis data.
Cancer mortality risks for individuals who were employed at nuclear facilities in Tarapur and for their respective family members with whom they lived were examined. Cancer deaths that occurred in this population between 1971 and 1988 were compared with death rates published by the Bombay City Cancer Registry. Risks were expressed as standardized mortality ratios (SMRs), which were computed by dividing the observed number of deaths by the expected number of deaths and multiplying this value times 100. There were 11 deaths from cancer among the employees, and this figure was too small to permit any trend analysis with respect to radiation exposures. The SMRs for all cancers and leukemia for male employees and for middle-aged male family members who were not exposed to any radiation were not statistically significant. A much larger database of person years at risk would be required to reach definite conclusions. The combined cancer risks for employees and families combined were similar to risks experienced by individuals in Bombay.
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