A Schiff base ligand (SBL), N2, N3-bis (anthracen-9-ylmethylene) pyridine-2, 3-diamine, was synthesized through the condensation of 2,6-diaminopyridine and anthracene-9-carbaldehyde using a 1:2 ratio. 1H NMR spectra confirmed the observation of non-involvement aromatic carboxylic proton in SBL. A novel series of lanthanide (i.e., praseodymium (Pr), erbium (Er), and ytterbium (Yb))-based SBL metal complexes was successfully synthesized, and their functional groups were elaborately demonstrated using UV–visible, Fourier transform infrared (FT-IR), and fluorescence spectroscopy analyses. FT-IR spectral studies revealed that SBL behaved as a bidentate ligand and it was structured with metal ions by the two azomethine nitrogens. The synthesized SBL-based metal complexes were elaborately performed for cytotoxicity activity versus Vero, human breast cancer (MCF7), and cervical (HeLa) anticancer cell lines.

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The Lanthanum loaded CuO (LCO) nanoparticles (NPs) were successfully synthesized by precipitationthermal decomposition method and characterized by X-ray diffraction (XRD), field emission scanning electron microscopy (FESEM), energy dispersive spectra (EDS), diffuse reflectance spectra (DRS), photoluminescence (PL), X-ray photoelectron spectroscopy (XPS) and BET surface area measurements. 10 The synthesized LCO NPs was used as nanocatalyst for the synthesis of 1, 4-disubstituted-1, 2, 3-triazoles by click reaction of substituted benzyl azides and alkynes and synthesis of propargylamines via threecomponent coupling reaction of aldehydes, alkynes and amines under ultrasonication. One-pot operation, atom-economical nature, regioselectivity and good yields are the noteworthy features of this protocol. The reusability of the prepared nanocatalyst was successfully examined six times without any appreciable loss 15 in catalytic activity.

DNA binding and photocleavage characteristics of a series of mixedligand complexes of the type [M(phen) 2 LL] n+ (where M = Co(III), Ni(II) or Ru(II), LL = 1,10-phenanthroline (phen), phenanthroline-dione (phen-dione) or dipyridophenazine (dppz) and n = 3 or 2) have been investigated in detail. Various physico-chemical and biochemical techniques including UV/Visible, fluorescence and viscometric titration, thermal denaturation, and differential pulse voltammetry have been employed to probe the details of DNA binding by these complexes; intrinsic binding constants (K b) have been estimated under a similar set of experimental conditions. Analysis of the results suggests that intercalative ability of the coordinated ligands varies as dppz > phen > phen-dione in this series of complexes. While the Co(II) and Ru(II) complexes investigated in this study effect photocleavage of the supercoiled pBR 322 DNA, the corresponding Ni(II) complexes are found to be inactive under similar experimental conditions. Results of detailed investigations carried out inquiring into the mechanistic aspects of DNA photocleavage by [Co(phen) 2 (dppz)] 3+ have also been reported.