Female patients (N = 107) were administered several psychological measures prior to routine dilation and curettage surgery using ketamine anesthesia to determine whether these measures were related to the psychotropic effects of ketamine. The psychological tests included measures of personality, perceived health, state-trait anxiety, and moods. The results showed that moods are more highly related to the psychotropic effects of ketamine than any of the other measures. Some form of counseling intervention that would better prepare patients to cope with the surgical situation might be effective in reducing this emotionality.