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The relation of myofibrillar hypoplasia to clinical splayleg was studied. A strain of Belgian Landrace sows was selected for this study because they produced pigs which had no myofibrillar hypoplasia. Myofibrillar hypoplasia could nevertheless by induced experimentally in these animals by dexamethasone treatment of the sows during late pregnancy. The lesion was observed without clinical signs and was compared to the myofibrillar hypoplasia in clinical cases of splayleg. The differences between these 2 groups may account for the appearance of clinical signs. These differences included the maturity of the myofibrils and the degree of autophagolysosomal glycogen breakdown.

Summary A neonatal congenital tremor (CT) syndrome that sporadically occurs in Belgian piglets is described. The results of an epidemiologic follow‐up survey on affected farms is presented. Experimental trials to provoke this syndrome by inoculation of a brain suspension, derived from CT‐piglets, in pregnant sows by intramuscular and intrauterine way, partly succeeded. Histological and biochemical studies on brain tissue of these piglets indicated that this form of CT should be classified as an A2 form. Using serologic and virologic examinations we were however not able to identify the probably infectious CT‐agent. Zusammenfassung Typ A2 Congenitaler Tremor beim Ferkel Es wird ein sporadisch in belgischen Schweinebeständen vorkommendes Syndrom mit congenitalem Tremor (CT) beschrieben. Die Ergebnisse einer entsprechenden epidemiologischen Untersuchung werden ebenfalls dargestellt. Versuche, das Syndrom durch intramuskuläre oder intrauterine Inokulation einer von CT‐Ferkeln stammenden Hirnsuspension bei den Ferkeln trächtiger Muttersauen zu induzieren, verliefen zum Teil erfolgreich. Nach histologischen und biochemischen Untersuchungen am Hirn dieser Ferkel dürfte es sich bei der betreffenden Form des CT um die Typ‐A2‐Form handeln. Mittels serologischer und virologischer Untersuchungen konnte jedoch das wahrscheinlich infektiöse CT‐Agens nicht identifiziert werden.

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