Aims: The present study aimed at assessing the effect of application of ice bag on pain during removal of femoral introducer sheath among patients undergoing interventional cardiology procedures. Dr. D Y Patil Hospital andSettings: Research Centre, Pimpri, Pune. Quasi experimental post-test control group design Sampling technique:Design: Methods and Material: Purposive sampling technique was used to select the samples. In this study, sample size was of 60, out of which 30 samples wereSample size: experimental group and 30 samples were in the control group. It is assumed that the pain will reduce on application of ice bag duringAssumption: removal of femoral introducer sheath. H : There will be a signicant difference in the pain score level after ice bag application on1Hypothesis: patients during removal of femoral introducer sheath. H : There will be an association between pain and clinical prole of patients with femoral2 sheath. The Investigator analyses the data using Descriptive and Inferential Statistics and presents them in tables,Statistical analysis used: graphs and gures. The following plan of analysis was done based on objectives. Result shows it is evident that the pain in experimentalResults: group had reduced signicantly as compared to that in the control group. The application of ice bag had an effect on pain during removal of femoral sheath. The study concluded that the application of ice bag during removal of femoral sheath had a signicant effect onConclusions: reduction of pain and therefore, it should be considered as a non-pharmacological measure in reducing pain.