Exotic Amino Acids. Part 1. Synthesis of α-Amino Acids with a Cyclohexene Substituent.-A new method for the preparation of the exotic, i.e unnatural, title amino acids (VI) (6 examples) from ylidene derivatives of Meldrum acid (I) using a cycloaddition-amination-Hofmann rearrangement strategy is developed. -(ZITSANE, D. R.; RAVINYA, I. T.; RIIKURE, I. A.; TETERE, Z. F.; GUDRINIETSE, E. YU.; KALEI, U. O.; Russ.

Exotic Aminoacids. Part 2. Reaction of 2-R-4-Methylcyclohex-4ene-1,1-isopropylidenemalonates with Some O-and N-Nucleophiles. -Reaction of the title cyclohexene-isopropylidenemalonates (I) with Oor N-nucleophiles proceeds with dioxane ring opening to furnish derivatives of cyclohexenemono-or -dicarboxylic acids depending on the basicity of the nucleophile and on the reaction temperature. -(ZITSANE, D. R.; RAVINYA, I. T.; RIIKURE, I. A.; TETERE, Z. F.; GUDRINIETSE, E. YU.; KALEI, U. O.; Russ.

New Convenient Method of Isopropylidene Methylmalonate Synthesis. -Isopropylidene methylmalonate (II) is obtained by reduction of malonate (I) with sodium borohydride in methanol. -(ZITSANE, D. R.; GUDRINIECE, E. YU.; RIJKURE, I. A.; KALEJS, U. O.; Chem. Heterocycl.

No abstract

Bromieren der leicht zugänglichen Indazole (I) mit N‐Brom‐succinimid in Tetra chlorkohlenstoff liefert die 7‐Brom‐Verbindungen (II), die mit Natriumazid in die 7‐Azido‐Verbindungen (III) übergehen.