Introduction: Blood transfusion is a life-saving procedure, but it has its own risks, both noninfectious and infectious complications. One packed RBCs unit believed to raise the levels of hemoglobin by 1 g per dl and hematocrit by 3 percent. Each patient should be dealt on an individual basis with assessment of the clinical signs and symptoms, in consideration to haemodynamic instability, comorbidity and the risk of further blood loss.Objective: 1.To study the change in hemoglobin level and hematocrit after the transfusion of single unit packed cell 2. To analyze any difference in rise in hemoglobulin and hematocrit based on age, gender and pretransfusion hemoglobulin concentration. Materials And Methods: The study is a retrospective study conducted in the blood bank of Chettinad hospital & research institute. All the recorded data for a period of 6 months from January 2019-June 20l9 were retrieved. All the patients, who were transfused single unit of packed cell with clinical details and other hemoglobin investigations in the study in our hospital, were included in the study. Patient without proper clinical and hematological investigation, neonates and children were excluded. Institutional ethical clearance was obtained before the commencement of the study. Statistical analysis was done using SPSS software and the results were expressed as mean and standard deviation. One way ANOVA test was performed between variables and a p value of <0.5 is considered significant. Results: During the study period 1289 transfusions were done in our hospital for various reasons. Of these 222 were single unit packed cell transfusions. The mean age is 48.05±16.48. The male: female ratio is 1.43. The mean rise in hemoglobulin and hematocrit in general, males and females are 1.04 & 2.84,

Background:  It is the prime duty of transfusion services to provide safe, adequate and timely need of blood and the blood products. Understanding the reasons for donor deferral can help in planning more efficient recruitment strategies and educate and motivate temporarily deferred donors in order to maintain a safe and adequate supply of blood products. Aims of the Study: To evaluate and analyze the blood donor deferral pattern in a tertiary care hospital blood bank and to review its influence on blood safety. Methodology: This retrospective study was conducted in the blood bank, CHRI from the year January 2015 to December 2018. Data like demographic data, clinical history, physical examination, haematological examination, stored in the blood bank was retrived. The donors will be deferred based on standard WHO guidelines. The collected deferral data was analyzed using SPSS software 2011version 20. Results: During the study period there were 7010 registered blood donors. The deferral rate was 5.19%. Among the donor deferrals, females were more commonly deferred ie 31.66%. The deferral rate among voluntary and replacement donors are 4.71% and 11.62% respectively. The rate of permanent deferral (17.86%) was less compared to temporary deferral (82.14%). Among temporary deferral anaemia is the most common cause (27.75%). Seropositive for Hepatitis B is the most common cause for permenant deferral (52.30%). Conclusion: In our study temporary deferral is higher this necessities the need of education, motivation of these donors for future donation to maintain a healthy and safe donor pool.