One of the most common diseases of the organ of vision is uveitis of various etiologies, characterized by a violation of the blood-ophthalmic barrier, and, as a result, the development of destructive and often irreversible processes in the iris, choroid, retina and vitreous body, which negatively affects the quality of vision and may lead to its complete loss.The article presents data on clinical cases of uveitis of exogenous and endogenous origin in dogs. A set of general and special diagnostic measuresophthalmic and biomicroscopy of the eye, biochemical studies, diagnostic criteria for assessing the state of the vascular tract were carried out. Based on the data obtained, a complex of therapeutic measures in dogs with uveitis was carried out and their effectiveness was evaluated.The research indicates that all dogs are prone to the disease, regardless of breed or age. The causes of uveitis were traumatic factorspurulent keratitis, open injuries and ulcers of the cornea (exogenous uveitis); and uveitis on the background of internal diseasesrenal failure, hepatitis or pancreatitis (endogenous uveitis). Clinical studies diagnosed a mild, moderate and severe degree of development of the disease, which in all cases were characterized by blepharospasm, photophobia, lacrimation, corneal edema and conjunctiva of the eye. Specific clinical signs of the disease have also been identified. In all cases, a pain response, miosis, iris edema, Tyndall effect, pericorneal injection of blood vessels were recorded. With the development of severe endogenous uveitis, clouding of the vitreous body was found in 22,2% of cases. Hyphema, precipitates, hypopion, fibrin accumulation in the anterior chamber of the eye were diagnosed in 33,3% of dogs with severe illness, both endogenous and exogenous in origin. With exogenous mild to moderate uveitis, changes in the deep structures of the eye were absent.The influence of systemic diseases of the body (hepatorenal syndrome, renal failure) on the development of endogenous uveitis is based on changes in the blood serum of such indicators as ALT, AST, alkaline phosphatase, urea and creatinine.All dogs underwent complex treatment taking into account the peculiarities of the course of uveitis. The use of uveitis mydriatic (atropine 1%), steroidal and non-steroidal antiinflammatory drugs (Dexamethasone 0,1% and Diftal 0,1%), antibiotics (novocaine-antibiotic retrobulbar blockade, Phloxal 0,3%), immunostimulants (Cycloflora) in the drug therapy regimen) and antioxidants (Ascarutin) made it possible to achieve disease remission in 83,3% of dogs.

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The purpose of the work was to research the etiological factors of perforation of esophagus, the clinical condition of animals, and also to perform a technique for surgical intervention to restore the function of the esophagus. The technique of operative access and the imposition of strong, airtight sutures was developed to contribute to the restoration of the esophagus function. The investigation object was three goats with bitten lacerations complicated by perforation of the esophagus in the cranioventral part of the neck, a horse with perforation of the esophagus in the middle part of the neck. The operating field in animals with damage of esophagus was prepared taking into account mechanical and chemical antiseptics, and local infiltration anesthesia was performed. The necrotic edges of the wounds excised, the skin dissected by 12-15 cm, and the neck muscles moved and separated in relation to each other, fixed with wound hooks and provided access to the perforated section of the esophagus. On the detected defects of the esophagus a polymer tube inserted into the cavity of the esophageal tube through the wound openings in the cranial direction until it exited the oral cavity by 10-15 cm, and then along the esophagus, than shifted towards the stomach. Thus, we obtained such a configuration and clear contours of the esophagus, which would facilitate the possibility of controlling the layer-by-layer application of surgical sutures and closing the perforation of the esophageal walls. The first level of Schmiden sutures applied to the mucous and muscle layers. Subsequently, for reliability three intermittent knotted seams imposed on the same layers. The second floor of the sutures – intermittent knotty was placed on the muscles and the adventitious layer of the esophagus (polymer suture material No. 4-6). Thus, a hermetic closure of the perforated defects of the esophagus was achieved. The wound was treated with antibacterial drugs and, first, an interrupted knotted suture was placed on the muscles and then on the muscles and skin. The resin tube removed through the oral cavity. In the postoperative period the neck was restricted in movement by applying wooden corsets for 5-6 days. The wound was treated with antibacterial drugs for 7 days. Feeding was carried out with chopped food, watering in small doses for two weeks. Regeneration of the operating wounds took place without complications due to primary intention. In 6-8 weeks after surgery the clinical condition of the animals was within normal limits, the animals were fed normally.

A special role in the statics and dynamics of locomotor apparatus in horses is played by the functional state of the hoof. The hoof in horses has a rather complicated anatomicalmorphological structure, but performs a multifunctional action. This tends to distal limbs until many diseases occur in them. The most common and most dangerous hoof disease in horses is laminitis, which is approximately 41% of other diseases of the hoof. The article presents data on clinical cases of horses laminites. The etiological factors of occurrence of the disease are analyzed, clinical signs are described, a complex of diagnostic measures was carried outgeneral and special clinical researches, radiological, laboratory, and also treatment of patients with horses.