Hypertension is an increasingly important medical and public health burden globally. Worldwide, hypertension is estimated to cause 7.7million deaths, which is about 12- 15% of all total deaths. In recent years a various models of calcium metabolism involving cellular calcium level, membrane binding transport, altered permeability and transport kinetics have been described in individuals with hypertension and in animal models as well. The objective for identifying variations in levels of calcium and phosphorus in hypertensive patients helps to address and reduce risk of Cerebrovascular disease, Coronary artery disease, Chronic kidney disease and Peripheral vascular diseases and thereby morbidity and mortality worldwide. In this study, we attempt to review the evidence that calcium metabolism, thereby change in serum calcium levels that are implicated in primary hypertension in patients visiting medicine OPD and admitted under Department of Internal medicine in Mahatma Gandhi Memorial Hospital, Warangal.