It is generally accepted that the increased cardiovascular morbidity and mortality in hypertension are related to target organ damage. Classically, the target organs are heart, brain, and kidneys. This brief report examines whether high arterial pressure may also affect other organs, such as aorta and large arteries. An attempt was also made to elucidate the relationship between disorders of the aorta and large arteries and other cardiovascular risk factors to the pathophysiology and treatment of patients with hypertension and its severe comorbid disease, atherosclerosis.

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Bei 113 Infarktpatientcn wurden die Serumharnsäurewerte untersucht. 48,8% hatten eine Hyperurikämie von mehr als 6,4 mg/100 m/. Die Verteilungskurve zeigt ein trimodalcs Verhalten und eine signifikante Abweichung vom theoretisch ermittelten Kurvenverlauf. Möglicherweise liegt ein genetischer Polymorphisms vor, der Beziehungen zur Infarktgencse hat. Serum uric acid values from 113 patients after heart infarctUric acid levels were measured in the sera of 113 patients with heart infarct. 48.8% had a hyperuricaemia of more that 6.4 mg/100m/. The distribution curve showed a trimodal behaviour and a significant deviation from the theoretical curve. There possibly exists a polymorphism, which has a relationship to the genesis of infarct.

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