The process of effective decision-making in the framework of integrated regional development programs is based on the rational use of resources. However, in the situation of international competition, socio-economic development of the region becomes less dependent on the amount of natural resources. The most important resource within the geographical territory is the population living on it -a number of people which is put together in the process of social production and consumption. Labor potential is formed under the influence of the whole complex of social and economic factors.The main factors reflecting the status of workforce potential used in the present study were: labour force share in the proportion of the total population; the proportion of actively working population; the proportion of employed in the total labor force; the proportion of employed in the total workforce in the key sectors; the rate of unemployment.The analysis of labor force potential of the Republic of Tatarstan resulted in possibility to divide all administrative regions into 5 groups. These are the regions characterized by a high level of labor force potential; regions with an above average level of labor force potential; regions which are said to have an average level of labor force potential; regions with a below average level of labor force potential; regions characterized by a low level of labor force potential [6].