Background Periodontitis is a multifactorial inflammatory disease of tooth supporting tissues caused by oral biofilms, influenced by environmental and genetic factors, among others. Ethanol consumption has been considered a factor that enhances alveolar bone loss, especially in high doses. The present study aims to investigate the changes promoted by ethanol binge drinking per se or associated with ligature-induced periodontal breakdown on alveolar bone loss. Materials and methods Thirty-two Wistar rats were randomly allocated into four groups: control (C), ethanol (3g/kg/day; 3 days On-4 days Off protocol by gavage for 28 days, EtOH), experimental periodontitis (EP) and experimental periodontitis plus ethanol administration (EP+EtOH). On day 14 th , periodontitis was induced by ligatures that were placed around the lower first molars. On day 28 th , the animals were euthanized and mandibles were submitted to stereomicroscopy for exposed root area analysis and micro-computed tomography (micro-CT) for the evaluation of alveolar bone loss and microstructural parameters. Results The results revealed that ligature-induced alveolar bone loss is aggravated by ethanol binge drinking compared to controls (1.06 ± 0.10 vs 0.77 ± 0.04; p<0.0001). In addition, binge drinking per se altered the alveolar bone quality and density demonstrating a reduction in trabecular thickness, trabecular number parameter and bone density percentual. Periodontal disorder plus ethanol binge drinking group also demonstrated reduction of the quality of bone measured by trabecular thickness. Conclusions In conclusion, intense and episodic ethanol intake decreased alveolar bone quality in all microstructural parameters analyzed which may be considered a modifying factor of periodontitis, intensifying the already installed disease.
A automação e supervisão de sistemas tem sido crescente, propiciando o aumento da comodidade e confiabilidade, bem como o reduzido gasto de processos. Vinculado a aplicativos web com interface amigável, os sistemas automatizados proporcionam a eficientização de sistemas elétricos de edificações com extrema praticidade. Após o desenvolvimento de um sistema de automação de baixo custo, este artigo apresenta o desenvolvimento de uma aplicação web capaz de gerenciar um sistema automatizado de iluminação elétrica a partir de diferentes dispositivos com acesso à internet. Como estudo de caso, o trabalho apresenta o impacto da automação associado ao aplicativo web no consumo e custo de energia elétrica de um edifício de uma instituição de ensino público.
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