BackgroundExtracorporeal organ assist devices provide lifesaving functions for acutely and chronically ill patients suffering from respiratory and renal failure, but their availability and use is severely limited by an extremely high level of operational complexity. While current hollow fiber‐based devices provide high‐efficiency blood gas transfer and waste removal in extracorporeal membrane oxygenation (ECMO) and hemodialysis, respectively, their impact on blood health is often highly deleterious and difficult to control. Further challenges are encountered when integrating multiple organ support functions, as is often required when ECMO and ultrafiltration (UF) are combined to deal with fluid overload in critically ill patients, necessitating an unwieldy circuit containing two separate cartridges.MethodsWe report the first laboratory demonstration of simultaneous blood gas oxygenation and fluid removal in single microfluidic circuit, an achievement enabled by the microchannel‐based blood flow configuration of the device. Porcine blood is flowed through a stack of two microfluidic layers, one with a non‐porous, gas‐permeable silicone membrane separating blood and oxygen chambers, and the other containing a porous dialysis membrane separating blood and filtrate compartments.ResultsHigh levels of oxygen transfer are measured across the oxygenator, while tunable rates of fluid removal, governed by the transmembrane pressure (TMP), are achieved across the UF layer. Key parameters including the blood flow rate, TMP and hematocrit are monitored and compared with computationally predicted performance metrics.ConclusionsThese results represent a model demonstration of a potential future clinical therapy where respiratory support and fluid removal are both realized through a single monolithic cartridge.

Purpose: This study investigated Allied Health Practitioners’ (AHPs) perspectives on and consensus of clinical supervision in an acute tertiary hospital in Singapore. Specifically, AHPs’ views on the benefits of and barriers surrounding engaging in clinical supervision, as well as strategies for enhancing clinical supervision experience. Method: A Delphi approach utilizing a two-round process via online questionnaires was employed. A total of 77 AHPs responded to the first round of the Delphi questionnaire and 55 AHPs completed the second round (71% retention rate). Open-ended responses from the first round underwent thematic analysis and resulted in sixty statements (five themes) describing engagement in clinical supervision. In the second round, AHPs were asked to rate each characteristic of clinical supervision on a 5 point Likert Scale. Results: Consensus was reached on 52 statements using a cut off of greater than 68% positive respondents and an interquartile deviation (IQD) ≤1. The study identified 52 statements considered important for successful clinical supervision for AHP in an acute tertiary hospital in Singapore. Conclusions: The themes and underpinning statements provide insights about clinical supervision in the Singapore hospital setting.