This study aimed to observe the therapeutic effects and adverse reactions of radiofrequency thermocoagulation combined with adriamycin injection in dorsal root ganglia on lung cancer rib metastasis-related refractory pain which has no response to conventional therapy.This study contained 27 patients with lung cancer rib metastasis-related moderate or severe pain which had no response to conventional therapy. Under computed tomography (CT)-guidance, radiofrequency puncture need reached the corresponding intervertebral foramens to ensure needle point near dorsal root ganglia (DRG) by sensory and motor stimulation tests, and then radiofrequency thermocoagulation was performed on each corresponding DRG followed by injection of 0.5 to 1 mL of adriamycin (0.5%). The conditions of pain and complications were observed before management and 3 days, 1 month, and 3 months after management, respectively.Numerical rating scale (NRS) scores and dosage of morphine were all significantly decreased after management as compared with those before management (all P < 0.01). Although the number of patients with chest wall numbness was significantly increased after management as compared with that before management (all P < 0.01), the degree of chest wall numbness was tolerable. There were no statistical differences between before and after management in nausea and vomiting, and constipation.CT-guided radiofrequency thermocoagulation combined with adriamycin injection in DRG can effectively control lung cancer rib metastasis-related pain which has no response to conventional therapy. This combinatory treatment regimen is featured by better therapeutic effects and a few complications, so it is worthy of being recommended in clinical application.

Original BSS (blind source separation)-based speech encryption system utilizes BSS to perform decryption, but the complexity of BSS algorithms limits the decryption speed and its real-time application. Correlation calculation is an algebraic decryption method originally proposed for BSS-based image cryptosystem to overcome two limitations of BSS: permutation and scaling ambiguity and difficulty for separating strongly correlated images. Considering that there is similarity between encryption matrix for speech encryption and image encryption, this paper analyzes the correlation of speech signals with key signals, and then utilizes the correlation calculation to achieve speech decryption. The experiment results show that correlation calculation decryption nicely simplifies BSS-based speech encryption system, largely speeds up the speech decryption, and slightly improves the quality of decrypted speech signals.

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