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In the 1990s, skin island flaps supplied by the vascular axis of sensitive superficial nerves, like the sural and saphenous nerves, were introduced. Flaps supplied by the superficial peroneal nerve accessory artery (SPNAA), however, are still not commonly used. The aim of this study is to understand the anatomical structure of the SPNAA and its perforators in the anterior intermuscular septum, and to utilize SPNAA perforator flaps in the clinic.We dissected sixteen cadavers and assessed the location and number of the SPNAA, its perforators, and the septocutaneous perforators originating from the anterior tibial artery. A SPNAA perforator flap was applied to twelve patients, the free flap was applied to eleven patients, and the pedicled flap was applied to one patient.SPNAA varied from 7 to 16 cm in length with an average of 4.5 perforators to supply lateral aspect. An average of 3.13 septocutaneous perforators originated from the anterior tibial artery. The mean size of the SPNAA perforator flaps was 65.5 cm 2 . The complete follow-up period was 3-20 months. Although one flap was lost as a result of arterial thrombosis, the procedure was successful in the remaining eleven patients. In addition, reduced flap thickness made them more aesthetically appealing.SPNAA perforator flaps could be an excellent alternative to perforator flaps that use the lower leg as a donor site.

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Loss of heterozygosity (LOH) has been established as an important genetic mechanism giving rise to malignant neoplasia. The mechanism of LOH has been shown to cause basal cell carcinoma and malignant melanoma as well as other types of skin cancer. A few studies on LOH in sporadic keratoacanthomas have been reported. The purpose of this study was to investigate the significance of LOH in the pathogenesis of sporadic keratoacanthomas developed in 10 Korean patients. The presents of LOH at 7 microsatellite markers (D2S286, D3S1317, D5S346, D9S160, D9S171, D10S185, and D17S261) were evaluated in sporadic keratoacanthomas. LOH was found in only 1 of 10 cases at D10S185. The low frequency of LOH detected in this study suggests that LOH may not be significant in the induction of sporadic keratoacanthomas.