The development of COVID-19 vaccine is highly concerned by all countries in the world. So far, many kinds of COVID-19 vaccines have entered phase III clinical trial. However, it is difficult to deliver COVID-19 vaccines efficiently and safely to the areas affected by the epidemic. This paper focuses on vaccine transportation in a supply chain model composed of one distributor and one retailer (clinic or hospital), in which the distributor procures COVID-19 vaccines from the manufacturer and then resells them to the retailer. Distributor detects the activity level of the vaccines, and retailer is responsible for transportation of the vaccines. Firstly, we establish a difference equations model with time-delay. Secondly, we investigate the impact of time-delay on the stability of vaccine supply chain. In addition, we explore the influence of decision adjustment speed of the distributor (or retailer) on the stability of vaccine supply chain. Finally, we verify the theoretical results by a two-dimensional bifurcation diagram, the largest Lyapunov exponent, entropy, and domain of attraction. The results show that when the decision delay-time or the adjustment speed of decision variables exceeds a certain threshold, it brings a negative impact on the stability of vaccine supply chain system. The stability domain of the system shrinks as customers’ sensitivity to cold chain transportation decreases and by contrast expends as customers’ sensitivity to vaccine prices decreases. When the vaccine supply chain is in a state of chaos, the effect of external control over the system is superior to that of internal control over the system.

This paper constructs a continuous dual-channel closed-loop supply chain (DCLSC) model with delayed decision under government intervention. The existence conditions of the local stability of the equilibrium point are discussed. We analyze the influence of delay parameters, the adjustment speed of wholesale price, recovery rate of waste products, direct price, carbon quota subsidy, and carbon tax on the stability and complexity of model by using bifurcation diagram, entropy diagram, attractor, and time series diagram and so on. Besides, the delay feedback control method is adopted to control the unstable or chaotic system effectively. The main conclusions of this paper show that the variables mentioned above must be within a reasonable range. Otherwise, the model will lose stability or enter chaos. The government can effectively adjust manufacturers' profit through carbon tax and carbon quota subsidy, and encourage manufacturers to reduce carbon emissions and increase the remanufacturing of waste products.

Due to the important role of the vaccines in the prevention of global epidemics, this paper focuses on a vaccine transportation supply chain composed of one distributor and one retailer. Based on the assumption that the decision-maker does not make a decision instantaneously, we present a decision-making time-delay model. Firstly, we captured some sufficient conditions of delay-induced bifurcation for the model by regarding different combinations of the decision delay periods as the bifurcation parameters and analyzed how the speed of decision-making adjustment of distributor or retailer affects the critical point of system stability. Secondly, we made a numerical simulation on the model by using a two-dimensional bifurcation diagram, largest Lyapunov exponent, and entropy and chaotic attractor, respectively. Finally, we used two coordination methods to control chaos and compared them. The results show that when the decision delay exceeds a certain threshold, the system will lose stability or go into chaos. The precipitous speed of decision variable adjustment of the distributor or retailer will increase the entropy of the system and lead the system into a chaotic state. When the vaccine supply chain is in chaos, the effect of external control on chaos is better than that of internal control on chaos.