Nebulization solutions contaminated with microorganisms can be sources of infection.1-7) However, since nebulization solutions are classified as external preparations, their hygienic management tends to be neglected at present. [8][9][10][11][12] We investigated the microbial contamination of nebulization solutions in use from ultrasonic nebulizers commonly used in nebulizer therapy. In addition, the methods of preventing the microbial contamination of these nebulization solutions were evaluated.

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We investigated the correlation of peak inspiratory ‰ow (PIF) with peak expiratory ‰ow (PEF) in 29 bronchial asthma patients, and the improvement of inhalation technique with a dry powder inhaler (DIP) before and after medical consultation in 3 patients. There was a signiˆcant positive correlation (R＝0.772, p＜0.001) between PIF and PEF in asthmatics. Furthermore, PIF and PEF the values were low in elderly women with combined complications of emphysema. Two of 3 patients who had experienced the problem of residual medicine improved their inhalation technique after the medical consultation compared with before. These results indicate that the clinical examination of PIF and PEF and medical consultation on inhaled steroid use in bronchial asthma patients could be important.

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