The integration of faith and learning (IFL) is an integral part of Christian higher education. The recent years have seen a spate in published studies testifying to an intense pursuit of meaningful IFL by many institutions of Christian higher education. However, little scholarship has been devoted to explore the influence of faith integration in science and its effect on the spiritual growth of students. A private, Christian university in the Southwest United States, has integrated the Christian worldview (CWV) in at least 30% of courses in college programs. Instilling the core Christian convictions into each student’s total college life has been one of the distinctive tasks of the University. The purpose of this study is twofold: (1) to understand how CWV develops in Biology and (2) how IFL affects the personal faith of students. The data was collected, over a period of three consecutive years 2016 to 2018, from students preparing for Health Care and Science careers. Using the survey design with open-ended questions, 489 participants provided responses to articulate the Christian worldview perspective of microorganisms and diseases. Findings reveal a positive impact of IFL on the personal faith of students. The results also indicate students demonstrating growth in their understanding of the biblical worldview within the context of Biology.