Background:Alopecia is one of the most important hair follicle (HF) disorders, which is divided into scarring (cicatricial) and nonscarring (noncicatricial) types.Objective:The aim of this study is to investigate the expression of stem cell (SC) markers such as cytokeratin (CK) 17 and CK19 in scarring and nonscarring alopecia.Materials and Methods:Thirty patients with scalp alopecia (15 with scarring alopecia and 15 without) together with ten healthy volunteers were included in this study. Biopsies were taken from all participants and stained for CK17 and CK19 using immunohistochemistry.Results:There was a statistically significant difference between the nonscarring group and the control group with regard to CK17 expression in the outer layers of the HFs (P = 0.00) and CK19 staining of the inner layers of the HFs (P = 0.008). There was a statistically significant difference between the scarring and the control groups regarding CK17 expression in the outer (P = 0.00) and the inner layers (P = 0.00) of the HFs and CK19 expression in the inner layers of the HFs (P = 0.00). CK17 expression in the outer layers (P = 0.02) and the inner layers of the HFs (P = 0.00) together with CK19 expression in the inner layers of the HFs (P = 0.00) showed statistically significant differences between scarring and nonscarring alopecia groups.Conclusions:The presence of SC markers (CK17 and CK19) in the HFs was affected in both scarring and nonscarring alopecia, but the defect in scarring alopecia is more evident than that of nonscarring alopecia. The persistence of SC markers in some types of scarring alopecia could give a hope for the recovery of these lesions. Further studies are recommended to clarify the benefit from using HF SCs in the treatment of alopecia.

Background: Revision rhinoplasty is reported to occur in 8% to 15%. Reoperation should be performed to correct deformities that were not diagnosed or addressed in previous surgeries, such as those from poor planning, performance and poor surgical healing. The aim of the study was to evaluate the problem of each case seeking revision rhinoplasty and different modalities for management to reach satisfactory results.Methods: This is a prospective study which was done in plastic surgery department, Menoufia University Hospitals over the period from December 2017 to December 2019. The study included 31 patients underwent previous rhinoplasty.Results: Patients were selected from the outpatient clinic, 31 patients who had varieties of nasal deformities. Mean age of the patients was 31.7 years. Female represent the majority of patients by 80.60% and males were 19.40% with significant difference in satisfaction (p=0.05). Patient satisfaction after surgery and it was excellent for 14 cases (45.20%), good for 9 cases (29 %) and it was fair in 8 cases (25.8%). Rhinoplasty outcome evaluation (ROE) score was correlated with patient satisfaction grades as mean of ROE score in excellent group was 67.5; in good group was 58.3; while in fair group was 38.8 with significant p value (0.001).Conclusions: Excellent patient satisfaction is related good planning, close follow up time, and less complication. Cartilage grafts especially rib cartilage is considered a lifeboat for revision rhinoplasty. We can link grades of patient satisfaction to ROE score.