This is the first and only seroprevalence study of COVID-19 conducted in the general population in Algeria prior to the national vaccination campaign against COVID-19. The significance of this study lies in its contribution to our understanding of the spread of the virus in the population before the implementation of the vaccination program.

Background: Accidents exposing to blood AEB represent real public health problem in healthcare establishments. The objective of our study was to estimate the frequency of AEB As at our establishment as well as the risk factors that determine their occurrence. Patients and Methods: A cross-sectional descriptive survey was conducted at a hospital university establishment over period from October 16 to December 3, 2018. The survey concerned accident exposing blood to the staff of our establishment. Data entry and analysis was carried out using Epi-Info software. Results: A clear predominance of women was noted (79.2%) among the study population with a Sex ratio equal to 0.26. The average age was 27.7 ± 6.2 years.The frequency of exposure to AEB among hospital staff was 48.5%. Needlestick injuries were the most common accident (88.3%), followed by splashing blood or body fluids (51.7%), and cutting with a sharp object (10.0%). Among the risk factors significantly associated with the occurrence of AEB, we can cite the medical profession (OR = 3.94; p<0.001), the surgical specialty (OR = 3.3; p <0.01), the male sex (OR = 3.7; p <0.01). Likewise, risk of AEB increased significantly with age (p <0.01) and professional seniority (p <0.02). Keywords: Accidents exposing blood; hospital staff; Algeria.

Severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2) is a new, highly contagious virus causing serious emerging coronavirus disease (Covid-19), it quickly spread globally, causing a pandemic with a large number of deaths and millions of confirmed cases, posing a serious threat to global public health. Algeria was also caught up by the pandemic; the first indigenous outbreak was notified on March 01, 2020, thus announcing the effective start of the epidemic. Despite the significant progress made by scientists on the basis of various studies and clinical trials, there is currently no specific cure. But the prospect of a preventive or therapeutic vaccine seems increasingly realistic thanks to more intense global cooperation and also by taking advantage of the data collected on SARS and MERS. However, much remains to be learned about immunity against SARS-CoV-2 including the protective immunity induced by vaccines and the maintenance of this immunity. Therefore, at this time, it is imperative to remain cautious about this virus and to pursue preventative methods to prevent its spread. Algeria very early in adapting with preventive measures which proved to be effective and led to a significant decrease in cases of contamination, especially in western Algeria. In order to provide a clear overview of the vast literature available, we conducted a review of the literature on the SARS CoV-2 and the disease (Covid-19), while addressing the epidemiological situation in Algeria.