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The paper proposes a new holistic model -the E-Learning Cube -with the aim to enable better understanding and characterization of the basic principles and mechanisms of E-Learning, for efficient use of the underlying infrastructure and a successful implementation strategy within Collaborative Networks. A short case study is presented in order to demonstrate how the new model was used for the implementation of an e-Learning system in a Collaborative Environment. Eventually the authors conclude with guidelines towards an ontology-based approach for e-Learning.

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