The purpose of this study was to examine the outcome after surgery for an acute Achilles tendon rupture. In particular, we wanted to study whether persons who have suffered an Achilles tendon rupture are at greater risk of a contralateral tendon rupture. From September 1990 to April 1997, 168 acute Achilles tendon ruptures in 26 women and 142 men were treated operatively. In August 1998 (median: 4.2 years post injury), 154 of these patients (92%) responded to a follow-up questionnaire. Local symptoms (pain, decreased strength and/or reduced range of motion) were reported pre injury by 25% of the patients; at follow-up this had increased to 52%. Ten patients (6%) experienced a rupture on the contralateral side during the follow-up period (OR: 176 [70-282] vs. the expected rate based on the general population risk of this injury, P<0.001). Thus, this study suggests that patients with an Achilles tendon rupture are at significantly increased risk of a contralateral tendon rupture, as well. Also, as many as half of the patients suffered from post-injury problems at long-term follow-up.
PurposeSince January 2015, all men referred to urologists in Norway due to elevated PSA or other suspicion of prostate cancer underwent multiparametric MRI (mpMRI) before prostate biopsy. At our hospital, patients and the initial MRI were assessed by an urologist and if deemed necessary, patients were referred to another institution for MR/US fusion biopsies. Before MR/US biopsy, patients underwent a second mpMRI. Since we noticed disagreement of these two mpMRIs before biopsy, we retrospectively assessed the level of agreement between the two mpMRIs from the two institutions.MethodsDuring the first 6 months of 2015, 292 patients were referred to our outpatient clinic. We referred 126 patients of these to the other institution for MR/US fusion biopsy. The 2 mpMRIs were performed within 4 weeks. We analyzed MR reports and schematics for number of lesions and highest PIRADS score per side of the prostate and histological result of the biopsies. Bland–Altman’s plot was used to compare the level of agreement between the two mpMRIs of the same patient before biopsy.ResultsThere was a poor level of agreement between the two mpMRIs and a statistically significant difference in PIRADS scores. Regression analysis showed that there was no proportional or systematic bias.ConclusionIn unselected patients with elevated PSA, there seems to be a significant variation of mpMRI results across institutions. The PIRADS scoring system needs to be validated with regards to MR equipment, mpMRI protocols and inter-reader variability of radiologists.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.