Background. Preoperative eye-covering training for 3 hours has been reported to e ectively reduce the incidence of emergence delirium (ED) in preschool children. However, most children can only maintain the eye being covered for less than 60 min, and shortening eye-covering duration can also achieve similar clinical e ects as long duration of eye-covering. is study was designed to compare the e ects of 30-min and 60-min eye-covering pretreatment based on cartoon education only on preoperative anxiety, postoperative ED, and pain score after ophthalmic surgery with general anesthesia in preschool-aged children. Methods. Preschool-aged children (3-7 years) who were diagnosed with cataract, blepharoptosis, trichiasis, strabismus, eyelid tumor, and underwent ophthalmic surgery with general anesthesia from August 2021 to January 2022 were recruited. A total of 228 patients were randomly assigned at a 1 : 1:1 ratio to receive 30-min eye covering (30-min group), 60-min eye covering (60-min group) pretreatment, or programmed education only (C group). e preoperative anxiety, postoperative emergence delirium, and pain were compared between the groups. Results. e preoperative anxiety score, postoperative ED score, and incidence of ED in the 30-min group (n 76) and 60-min group (n 72) were signi cantly lower than those in the C group (n 76), demonstrating a signi cant between-group di erence (P < 0.001). However, the 30-min group and 60-min group had no signi cant di erence in the abovementioned outcome measures (P > 0.05). Moreover, no signi cant di erence was found in postoperative pain scores among the three groups (H 0.274, P 0.872). Conclusion. Both 30-min and 60-min eye-covering pretreatments signi cantly reduce preoperative anxiety and postoperative ED after ophthalmic surgery with general anesthesia in preschool-aged children.e e ects of the two groups show no intergroup di erence, but the 30-min eye-covering pretreatment may be more convenient for practicing. Trial Registration. is study was registered with the No. NCT04973150.