Objective To study the impact of secondary mental disorders in patients affected with acromegaly and correlate them with quality of life (QoL) and disease status. Design An observational transversal descriptive and comparative study that evaluates QoL's impact due to secondary mental disorders in affected Mexicans with acromegaly using AcroQoL and SF‐36 instruments. Correlation of the results with the disease's biochemical status was performed. According to Beck's scales, anxiety and depression analyses evaluate QoL's impact, and its gender variability is described. Results Eighty‐five patients with diagnoses of acromegaly were included. The mean age was 43.18 years, 47 being women (55.29%). The mean age at diagnosis was 37.95 years, with no difference between men and women. AcroQoL and SF‐36 global and sub‐domain scores differed significantly between men and women, the latter having lower global and individual sub‐domain scores. The mean score of QoL, according to AcroQoL, is 59.40. In women, the mean values are less (55.13) than men (64.68), p = 0.021. The sub‐domain analyses’ scores in physical, appearance and social relationships were less in women (53.21; 47.34; 62.32) than men (62.68; 56.76; 73.87) p = 0.044, 0.069 and 0.013, respectively. Higher Beck's Depression Inventory (BDI) and Beck's Anxiety Inventory (BAI) scores correlated with lower QoL as assessed by global and individual sub‐domain scores. Women presented significantly higher BDI and BAI mean scores when compared to men regardless of their biochemical status. Anxiety (p = 0.027) and depression (p < 0.001) severity were higher in women compared to men. Conclusion Correlations between female gender, depression/anxiety scores and QoL require further validation. There is much to be routinely done to improve secondary psychopathology in patients affected by this disease. The need for mental status screening at diagnosis should be emphasized to identify secondary mental illnesses to improve QoL with its treatment.

Background: Although the essential components of pain pathways have been identified, a thorough comprehension of the interactions necessary for creating focused treatments is still lacking. Such include more standardised methods for measuring pain in clinical and preclinical studies and more representative study populations. Objective: This review describes the essential neuroanatomy and neurophysiology of pain nociception and its relation with currently available neuroimaging methods focused on health professionals responsible for treating pain. Methods: Conduct a PubMed search of pain pathways using pain-related search terms, selecting the most relevant and updated information. Results: Current reviews of pain highlight the importance of their study in different areas from the cellular level, pain types, neuronal plasticity, ascending, descending, and integration pathways to their clinical evaluation and neuroimaging. Advanced neuroimaging techniques such as fMRI, PET, and MEG are used to better understand the neural mechanisms underlying pain processing and identify potential targets for pain therapy. Conclusions: The study of pain pathways and neuroimaging methods allows physicians to evaluate and facilitate decision-making related to the pathologies that cause chronic pain. Some identifiable issues include a better understanding of the relationship between pain and mental health, developing more effective interventions for chronic pain's psychological and emotional aspects, and better integrating data from different neuroimaging modalities for the clinical efficacy of new pain therapies.

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Desde hace siglos el ser humano ha tenido la inquietud de registrar su cultura e historia. Pinturas rupestres, runas, papiros, códices, libros y en la actualidad internet, han sido testigos de nuestros adelantos en la ciencia y en la medicina. Dentro de los avances que han sido extremadamente importantes para la preservación de imágenes, destaca la fotografía.Gracias a los grandes adelantos, hoy existen múltiples plataformas en donde los humanos registramos nuestra vida, día a día y las cosas que son importantes para nosotros.En la medicina, la fotografía ha sido utilizada para el registro científico de casos clínicos y también para el aprendizaje de médicos en formación. Lo que antes era un dibujo que tomaba muchas horas e incluso días de realizar ha sido reemplazado por la fotografía que se puede obtener de manera instantánea.Además de las imágenes y videos, actualmente la realidad virtual, la realidad aumentada y la tercera dimensión son los avances más recientes. Desgraciadamente estas tecnologías no están disponibles para todos y requieren de un equipo humano y tecnológico costoso.El proyecto Photobrain nace de la necesidad de abolir la neurofobia e invitar al público general y especializado a conocer el sistema más interesante del cuerpo humano, el sistema nervioso. Esta iniciativa comienza durante el periodo de una residencia médica en que, a causa de la pandemia por covid-19, habían disminuido las cirugías, lo que estaba comenzando a mermar el entrenamiento. Así, se conjuntaron el hobbie de la fotografía con una gran pasión: la neurocirugía.Se empezaron a utilizar técnicas fotográficas, entre las que destaca el focus-stacking (apilado fotográfico), para generar imágenes de alta resolución del cerebro humano durante todas las etapas de la disección descrita en los años treinta por el doctor Klingler. Gracias al material producido fue posible crear redes sociales con causa e interesar a las personas en las neurociencias, con una metodología artística y simple. Conforme fue despertando el interés en los demás, también aumentó la curiosidad por explorar técnicas complejas como el 3D, la realidad virtual y la realidad aumentada.

It is important to understand the patient's vascular anatomy before treating cerebral aneurysms. The middle artery of the corpus callosum is one of the least common variations of the AComA complex. We describe the case of a 59-year-old woman who suffered a subarachnoid hemorrhage due to an AComA complex aneurysm that had ruptured. Fluorescein injection during the aneurysm clipping procedure revealed a partial obstruction of the middle artery, requiring repositioning of the clip. The vascular variations that our patients may exhibit at the time of aneurysm clipping must be kept in mind and understood.