ResumenUna nueva serie de compuestos de estructuras tipo 1,3-hexahidropirimidina se logró sintetizar, con el fin de comprobar y ratificar la reactividad del aminalmacrociclico: 1:3,7;9,13;15,19;21-tetrametilentetrahexahidropirimidina (TMTP) con fenoles para-sustituidos, empleando reacciones tipo Mannich en medio alcalino. Las estructuras se elucidaron por métodos espectroscópicos, las cuales mostraron compuestos consistentes con las estructuras propuestas. Los compuestos sintetizados no se encuentran reportados en la literatura consultada.
Palabras clave: bases di-Mannich, hexahidropirimidina, macrociclo, sustituido fenol
AbstrActA new series of compounds 1,3-type structures was achieved hexahydropyrimidine synthesize, checking and confirming the reactivity of 1:3,7,9.13,15.19, with for-substituted phenols, using Mannich type reaction in alkaline medium, structures were elucidated by spectroscopic methods, compounds which showed consistent with the proposed structures. The synthesized compounds are not reported in the literature.
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