A novel capillary action microfluidic viscometer has been designed that can measure the relative viscosity of a sample compared to a control liquid. Using capillary action circuits, the viscosity of a sample is transformed into a microfluidic bar-graph format without the use of external instrumentation. The bars in this case are represented by the distance that a liquid has flown through a microfluidic channel, relative to another liquid in an identical channel. As the device does not require external instrumentation, its use is targeted at point-of-care (PoC) situations. This implementation is made practical through capillaric Field Effect Transistors, and the conditional flow paths they enable. In this paper, we report on the design, operation, and performance of a two-channel version viscometer device exclusively based on capillary action circuits. Using poly-ethylene glycol solutions as viscous samples, we demonstrate that the device can transduce the relative viscosity consistently to within 2%. Enabled by the flexibility of the capillary action circuits, we additionally present a modified device which can measure transparent liquids without the need to add colorants to the sample. The forms of the device presented in this work have applications in both medical care and scientific measurements—particularly for PoC measurements.
Controlling fluid flow in capillaric circuits is a key requirement to increase their uptake for assay applications. Capillary action off-valves provide such functionality by pushing an occluding bubble into the channel using a difference in capillary pressure. Previously, we utilized the binary switching mode of this structure to develop a powerful set of fundamental fluidic valving operations. In this work, we study the transistor-like qualities of the off-valve and provide evidence that these structures are in fact functionally complementary to electronic junction field effect transistors. In view of this, we propose the new term capillaric field effect transistor to describe these types of valves. To support this conclusion, we present a theoretical description, experimental characterization, and practical application of analog flow resistance control. In addition, we demonstrate that the valves can also be reopened. We show modulation of the flow resistance from fully open to pinch-off, determine the flow rate–trigger channel volume relationship and demonstrate that the latter can be modeled using Shockley’s equation for electronic transistors. Finally, we provide a first example of how the valves can be opened and closed repeatedly.
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