Here we report a retrospective cross-sectional study on Esophageal eosinophilia (EsEo) frequency in Brazil, for 2, 425 pediatric patients with symptoms associated with gastroesophageal diseases in 2012. EsEo is defined by ≥15 eosinophils per high power field (400x) and confirmed through histological analyses of esophageal biopsies. Overall, 126 patients had EsEo equating to a frequency of 5.2%. There was a significant difference between the endoscopic features of patients with EsEo, where 10.7% had erosive esophagitis, 3.0% had non-erosive esophagitis and 1% showed normal esophageal mucosa. According to the interaction of the variables in the Classification and Regression Tree Analysis, most patients diagnosed with EsEo were older males with erosive esophagitis. On the other hand, the lowest frequency of EsEo was found among younger females with non-erosive esophagitis/normal mucosa. Environmental conditions, including climate variation and changes, were observed in association with EsEo, supporting a potential role for environmental factors in its pathogenesis. There was an inverse correlation between the number of EsEo, rainfall and humidity. EsEo is a relatively frequent finding in the pediatric population of Brazil with symptoms of gastroesophageal diseases. Both clinical and histological examinations of patients are important for a reliable diagnostic of EsEo cases and to patient care.

Objective: Humidity and temperature are fundamental for the balance in the life cycle of living beings and, consequently, for maintaining the well-being of the human population and reducing the prevalence of infectious diseases. Thus, in order to mitigate the impact of climate change, especially in the period when humidity is not the ideal, it is necessary to adopt some assistance measures. The present experimental study aims to elucidate what would be the recommended option to improve the quality of life of the human being and to clarify which resources (air humidifier, bucket of water or wet towel) will be effective to improve the humidity of the air in times of drought and low moisture. Methods: The experimental study was carried out with INKBIRD hygrometers allowing the analysis of the variation of air humidity throughout the day. Three forms of treatment were established: humidifier, wet towel and bucket of water. In each room, two hygrometers were placed equidistant from the occupant of the room and their respective treatment that varied between 1m and 2m away from the headboard indoor each room. In addition, two environments were used as controls, one being an external environment and the other an internal closed environment, totaling five rooms for the study. The rooms were monitored between the end of July and the end of August 2019 in Goiania (GO). Results: Although assistance measures are used to significantly improve air pollution in times of extreme drought, there was a significant difference between them. The humidifier and a wet towel had 7.50% and 5.71% more humidity in the external relation (external control), respectively, more efficient. The volume of water, however, did not show significant difference (p>0.05) and, therefore, there was no variation. Conclusion:The humidifier and the towel are treatments considered more efficient, and that there was a significant effect of distance on humidity. Therefore, 1m of distance is more efficient in increasing and/or maintaining air humidity, inducing improvements in the populations' health.

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