No abstract

Oral rehabilitation by dental implants is a routine treatment in the common dental practice, and volume reconstruction in cases of advanced alveolar ridge atrophy using bone autografts has become a frequently used therapeutic procedure. The study presents a histological evaluation of autogenous mandibular bone grafts integration in surgically created maxillary bone defects. Seven domestic adult dogs, Canis Familiaris were used in the study. Work methodology was established through maxillary and mandibular morphometry, the donor region being the posterior mandibular body, and the recipient region being the lateral body of the maxilla. In the experimental study, we simulated two bilateral maxillary bone defects, which were augmented with mandibular corticocancellous bone grafts. Biological samples containing the target areas were collected 90-100 days after grafting and the subsequent preparation method of the samples for histological analysis was the standard one.The histological results showed the successful integration and the beneficial effect of corticocancellous autogenous mandibular bone grafts applied in maxillary sites.

Chronic wounds have a long period of healing, being impeded by numerous factors, as infections. Polyhexanidine is a new broad spectrum antiseptic with non-toxic action which is used lately in wound cleaning solutions. A case control study was realized with two groups of patients treated with silver sulfodiazine and with polyhexanidine, the last group having an accelerated healing evolution. Besides the bactericide action, polyhexanidine has also no cytotoxicity, good tolerability and anti-inflammatory proprieties.

Merkel cell carcinoma is (MCC) a rare type of skin malignancy that appears as a result of a disorganized multiplication of the Merkel cells and has a high rate of recurrence and metastases even from early stages. We describe the case of an 84-year old women diagnosed with Merkel cell carcinoma of the lower lip. Surgical treatment was realised with tumor excision and reconstruction using advancement flaps. Postoperative cosmetic and functional results were excellent, but invasion of the lateral margins, the patient�s decision of refusing re-excision and delayed radiotherapy lead to a rapid recurrence within 3 weeks. Responsiveness to subsequent radiotherapy was very good with regression of the recurrent tumor and decreasing of the local discomfort. Surgical treatment Merkel cell carcinoma of the lip is sometimes very challenging for a surgeon due to the necessity of wide resection and of the patient�s cosmetic concern. Radiotherapy remained an efficient therapy of Merkel cell carcinoma and should be used as a single or adjuvant therapy in situations where surgery cannot be applied, cisplatin chemotherapy being used for metastasis.

No abstract