The analysis of lung sounds, collected through auscultation, is a fundamental component of pulmonary disease diagnostics for primary care and general patient monitoring for telemedicine. Despite advances in computation and algorithms, the goal of automated lung sound identification and classification has remained elusive. Over the past 40 years, published work in this field has demonstrated only limited success in identifying lung sounds, with most published studies using only a small numbers of patients (typically N<;20) and usually limited to a single type of lung sound. Larger research studies have also been impeded by the challenge of labeling large volumes of data, which is extremely labor-intensive. In this paper, we present the development of a semi-supervised deep learning algorithm for automatically classify lung sounds from a relatively large number of patients (N=284). Focusing on the two most common lung sounds, wheeze and crackle, we present results from 11,627 sound files recorded from 11 different auscultation locations on these 284 patients with pulmonary disease. 890 of these sound files were labeled to evaluate the model, which is significantly larger than previously published studies. Data was collected with a custom mobile phone application and a low-cost (US$30) electronic stethoscope. On this data set, our algorithm achieves ROC curves with AUCs of 0.86 for wheeze and 0.74 for crackle. Most importantly, this study demonstrates how semi-supervised deep learning can be used with larger data sets without requiring extensive labeling of data.

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Massive open online courses (MOOCs) promise to make rigorous higher education accessible to everyone, but prior research has shown that registrants tend to come from backgrounds of higher socioeconomic status. We study geographically granular economic patterns in ~76,000 U.S. registrations for ~600 HarvardX and MITx courses between 2012 and 2018, identifying registrants' locations using both IP geolocation and user-reported mailing addresses. By either metric, we find higher registration rates among postal codes with greater prosperity or population density. However, we also find evidence of bias in IP geolocation: it makes greater errors, both geographically and economically, for users from more economically distressed areas; it disproportionately places users in prosperous areas; and it underestimates the regressive pattern in MOOC registration. Researchers should use IP geolocation in MOOC studies with care, and consider the possibility of similar economic biases affecting its other academic, commercial, and legal uses.