Diseases caused by infections are becoming harder to treat as the antibiotics used become less effective. A combination of strategies to develop active biomaterials that enhance antibacterial effects are desirable, especially ones that cause fewer side effects and promote healing properties. The combination of nanotechnology with substances that have intrinsic antibacterial activity can result in the advance of innovative biomedical materials. In this sense, the goal of this work is to provide a summary of natural rubber latex materials obtained from the Hevea brasiliensis tree loaded with metallic and metal oxide nanoparticles. These nanoparticles have unique size-dependent chemical and physical characteristic that make them appropriate for use in pharmaceutical and medical devices, while natural rubber latex is a natural and biocompatible polymer with an intrinsic antibacterial effect. Moreover, we outline here the origin, extraction methods, and composition of natural rubber latex and different techniques for the synthesis of nanoparticles, including physical, chemical, and biological approaches. Finally, we summarize, for the first time, the state of the art in obtaining natural rubber-based materials with metallic and metallic oxide nanoparticles for biomedical applications.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.