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Herein, we report design, synthesis and spectral characterization of novel 4-ferrocenyl-8-(phenylthio)-1,2,3,4tetrahydroquinoline. Desired synthesis was achieved in three reaction steps, with a good overall yield (67%). First step included aza-Michael addition of 2-(phenylthio)aniline to 1-ferrocenylpropenone, subsequently, the obtained ketone was smoothly reduced to the corresponding 1,3-amino alcohol. The final step was an intramolecular cyclization prompted by acetic acid, proceeding via corresponding α-ferrocenyl carbocation. The synthesized compounds have been isolated pure, and their structure have been undoubtedly confirmed by standard spectral techniques (1 H NMR, 13 C NMR, IR and elemental analyses).

Chemical plants are generally associated with potentially high risk of chemical accidents. During chemical accidents hazardous substances jeopardize human lives, destroy material assests and degrade natural environment. The release of flammable and explosive gases or liquids especially poses a significant threat to the environment. This paper introduces the simulation of a chemical accident caused by an uncontrolled acetylene cylinder release in the warehouse of Messer Tehnogas Kraljevo chemical plant. The simulation was performed by ALOHA program package which defines a possible accident development and determines threat and safety zones. The assessment of potential scenarios is based on physico-chemical properties of the substance causing the accident. This paper discusses accident situations occurring under the most unfavorable atmospheric conditions.

This paper provides a report on an easily performable synthesis via one-pot reaction, between the newly synthesized 3-arylamino-1-ferrocenylpropan-1-ols and PhNCO. We have used the acetic acid as the catalyst and ultrasound irradiation as the reaction promoter. We have evaluated the reaction score on three examples. In order to gain a more comprehensive insight into the role of α-ferrocenyl carbocation, we have described a plausible mechanism of the transformations in question. Moreover, we have purified the prepared by using column chromatography. Besides, we provide a detailed characterization of the new compounds (products and starting material), which was performed by IR, NMR and elemental analyses.