Mucormycosis is a life-threatening infection affecting patients with diabetes. It is an angioinvasive disease often resistant to treatment with a debilitating course and high mortality. Here, we report a case of a 45 year old woman with type 2 diabetes mellitus who presented to us with history of right-sided ptosis and facial palsy, and subsequently developed loss of vision and palatal palsy. She was in diabetic ketoacidosis. Nervous system examination revealed involvement of right second, third, fourth, sixth, seventh, ninth, and tenth cranial nerves, suggestive of Garcin syndrome. The hard palate had been eroded with formation of black eschar. Computed tomography of paranasal sinuses revealed right maxillary and ethmoid sinusitis, with spread of inflammation to infratemporal fossa and parapharynygeal neck spaces. Debridement of sinus mucosa was done, and culture of the same yielded growth of rhizopus species. Histopathological examination of the tissue showed angioinvasion and fungal hyphae suggestive of mucormycosis. She was treated with amphotericin B, posaconazole, and periodic nasal sinus debridement, but her general condition worsened after 8 weeks due to secondary sepsis and she succumbed to death.

Thromboembolism is a well-recognized complication of hematological malignancy. The incidence of symptomatic thrombosis at diagnosis is relatively low in AML (acute myeloid leukemia) patients, though its incidence increases on treatment with anthracyclines. We reported a case of 69 year old female with T2DM who presented with DVT and later on acute limb ischemia of the same lower limb. On hematological evaluation, she had leukocytosis and thrombocytopenia. Further evaluation revealed AML. Thromboembolism as a rare presentation of AML in adults with leukemic hyperleukocytosis has seldom been reported. In the absence of clear guidelines, early diagnosis and management are desirable.

We report a 16-year-old Indian boy diagnosed with Blue Rubber Bleb Nevus syndrome, which is a rare venous malformation that goes overlooked in most case scenarios. He had presented with long standing history of fatigue, melena with a past history of surgery for a vascular malformation and also had multiple bluish skin plaques. He was evaluated and was found to have iron deficiency anemia. Considering the history of melena, upper GI endoscopy was done, which revealed multiple vascular malformations, and so did colonoscopy. Patient was offered multidisciplinary team (MDT) approach involving Internal Medicine, Gastroenterology, Dermatology and Plastic surgery

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A 20-year-old primigravida at 8 weeks of gestation presented to us with history of drooping of the right upper eyelid. It was associated with pain over the upper part of right side of face. She had history of headache and giddiness 2 days back which subsided. There was no history of seizures, altered sensorium, blurring/ loss of vision, diplopia or hearing loss. She neither had sensory deficits nor weakness. Examination revealed complete third nerve palsy on the right side (Picture 1) with complete ptosis and loss of pupillary reflexes (Picture 2). Rest of the cranial nerves were within normal limits. Sensorimotor system was normal.