Automated methods for detecting clinically significant (CS) prostate cancer (PCa) in multi-parameter magnetic resonance images (mp-MRI) are of high demand. Existing methods typically employ several separate steps, each of which is optimized individually without considering the error tolerance of other steps. As a result, they could either involve unnecessary computational cost or suffer from errors accumulated over steps. In this paper, we present an automated CS PCa detection system, where all steps are optimized jointly in an end-to-end trainable deep neural network. The proposed neural network consists of concatenated subnets: 1) a novel tissue deformation network (TDN) for automated prostate detection and multimodal registration and 2) a dual-path convolutional neural network (CNN) for CS PCa detection. Three types of loss functions, i.e., classification loss, inconsistency loss, and overlap loss, are employed for optimizing all parameters of the proposed TDN and CNN. In the training phase, the two nets mutually affect each other and effectively guide registration and extraction of representative CS PCa-relevant features to achieve results with sufficient accuracy. The entire network is trained in a weakly supervised manner by providing only image-level annotations (i.e., presence/absence of PCa) without exact priors of lesions' locations. Compared with most existing systems which require supervised labels, e.g., manual delineation of PCa lesions, it is much more convenient for clinical usage. Comprehensive evaluation based on fivefold cross validation using 360 patient data demonstrates that our system achieves a high accuracy for CS PCa detection, i.e., a sensitivity of 0.6374 and 0.8978 at 0.1 and 1 false positives per normal/benign patient.
Battery lifetime prediction is a promising direction for the development of next-generation smart energy storage systems. However, complicated degradation mechanisms, different assembly processes, and various operation conditions of the batteries bring tremendous challenges to battery life prediction. In this work, charge/discharge data of 12 solid-state lithium polymer batteries were collected with cycle lives ranging from 71 to 213 cycles. The remaining useful life of these batteries was predicted by using a machine learning algorithm, called symbolic regression. After populations of breed, mutation, and evolution training, the test accuracy of the quantitative prediction of cycle life reached 87.9%. This study shows the great prospect of a data-driven machine learning algorithm in the prediction of solid-state battery lifetimes, and it provides a new approach for the batch classification, echelon utilization, and recycling of batteries.
LiNi0.5Co0.2Mn0.3O2 (NCM523) has become one of the most popular cathode materials for current lithium-ion batteries due to its high-energy density and cost performance. However, the rapid capacity fading of NCM severely hinders its development and applications. Here, the single crystal NCM523 materials under different degradation states are characterized using scanning transmission electron microscopy (STEM). Then we developed a neural network model with a two-sequential attention block to recognize the crystal structure and locate defects in STEM images. The number of point defects in NCM523 is observed to experience a trend of increasing first and then decreasing in the degradation process. The space between the transition metal columns shrinks obviously, inducing dramatic capacity decay. This analysis sheds light on the defect evolution and chemical transformation correlated with layered material degradation. It also provides interesting hints for researchers to regenerate the electrochemical capacity and design better battery materials with longer life.
Material characterization has been proved to be the most intuitive approach to understand the chemical composition, structure, and microstructure of materials, which is the basis of material design. One of the most important steps in material design is to extract the characteristics from an image, and find their associations with the material structure and properties. Therefore, in recent years, with the rapid development of machine vision algorithms, characterization images have attracted attention in the field of material characterization. Researchers use computer vision algorithms, such as image denoising and enhancement, to preprocess the representation image, image segmentation and classification to detect and separate each microstructure from the characterization image, and quantitatively analyze the properties of materials. Herein, the application of computer vision algorithms in material image representation is summarized and discussed. The latest and valuable views for experts and scholars in both computer vision and material grounds are presented. Thus, this review provides guidance for material exploration and promotes the developments of artificial intelligence in the field of materials.
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