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Background: Condyloma acuminatum (CA) or genital warts are sexually transmitted infections caused by human papillomavirus (HPV). It is estimated that CA occurs in >80% of reproductive age in many countries, with the most common subtypes being 6 and 11. Purpose: The aim of the study to reveal the high risk (HR)-HPV in various condyloma acuminata in Dr. Moewardi Hospital. Methods: This study was a cross-sectional analytical observational study that assessed data collection concurrently over time. Specimens were patients diagnosed with condyloma acuminatum, biopsies were performed, and immunohistochemical staining was also performed. The sampling technique used sequential sampling, and the inclusion criteria included patients who came to our hospital for treatment. Results: The majority of the male sample was MSM. According to HIV status, 6 (30%) male patients were found to be positive. Immunohistochemistry showed that 15% of the samples were HR-HPV. Statistical test results for HR-HPV and low-risk (LR) HPV were significant, p-value = 0.038. Conclusion: Condyloma acuminatum is a sexually transmitted infection that usually occurs at the same time as HIV infection. In our study all patients with HR-HPV were MSM.

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Kromoblastomikosis merupakan infeksi jamur profunda pada kulit dan jaringan subkutan yang disebabkan oleh jamur berpigmen atau jamur dematiaceous. Penyakit ini merupakan endemi di daerah tropis dan subtropis seperti Asia, Afrika, dan Amerika Latin. Kromoblastomikosis lebih banyak ditemukan pada laki-laki dewasa yang bekerja di area pertanian, tukang kebun, maupun tukang kayu. Diagnosis kromoblastomikosis ditegakkan melalui pemeriksaan kerokan kulit, kultur mikroskopik, atau ditemukan sel muriform atau medlar bodies pada pemeriksaan histopatologi maupun kultur. Gambaran klinis bervariasi, lesi awal berupa papul yang menyebar secara lambat selama beberapa bulan sampai tahun, kemudian lesi akan membentuk suatu plak dengan bagian tengah atropi. Banyak pasien tidak terdiagnosis pada tahap awal perkembangan penyakit dikarenakan tahap ini jarang terlihat. Pengobatan kromoblastomikosis meliputi pembedahan lesi awal dan terapi farmakologis dengan agen antifungal seperti itraconazole, yang paling umum digunakan dalam pengobatan kromoblastomikosis. Prognosis kromoblastomikosis tidak terlalu baik, kecuali pada lesi yang baru.

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