Diversity-oriented biosynthesis of a library of antimycin-like compounds (380 altogether) was accomplished by using multiplex combinatorial biosynthesis. The core strategy depends on the use of combinatorial chemistry at different biosynthetic stages. This approach is applicable for the diversification of polyketides, nonribosomal peptides, and the hybrids that share a similar biosynthetic logic.

No abstract

A two-dimensional octagonal quasiperiodic photonic crystal composed of alumina cylinders is prepared. The transmission spectra of the quasicrystal are measured in the microwave region for the TM wave. We find that the position and width of the band gap do not depend on the incident direction, while the band structure can appear for quite a small piece of the quasicrystal. Two types of waveguide, a straight guide and a bending guide with two sharp 90° corners, are fabricated by removing three rows of cylinders. The measured transmittances show that the guiding efficiency for both waveguides is high.

Recently, negative refraction of electromagnetic waves in photonic crystals was demonstrated experimentally and subwavelength images were observed. However, these investigations all focused on the periodic structure. Here, we report a new theoretical and experimental finding that negative refraction can appear in some transparent quasicrystalline photonic structures. The photonic quasicrystals (PQCs) exhibit an effective refractive index close to ÿ1 in a certain frequency window. The index shows small spatial dispersion, consistent with the nearly homogeneous geometry of the quasicrystal. More interestingly, a superlens based on the 2D PQCs can form a non-near-field subwavelength image whose position varies with the source distance. These properties make PQCs promising for application in a range of optical devices.