Introduction: Menopause, being a natural period associated with the cessation of ovarian function, is one of physiological stages in a woman's life. Epidemiological studies show that this is when women are at the greatest risk of depressive disorders. Other common conditions observed in menopausal women are various metabolic disorders, including type 2 diabetes. The aim of this study was to determine the relationship between climacteric and depressive symptoms in healthy women and those with type 2 diabetes. Materials and methods: This survey-based study involved 103 women aged 44-65 years, including 33 with type 2 dia betes. Research instruments were: the Kupperman Index for the severity of climacteric symptoms, and the Beck Depression Inventory for the severity of depressive symptoms. Results: The analysis did not reveal any statistically significant relationship between the severity of depressive symptoms and type 2 diabetes. At the same time, it demonstrated that the lack of energy dependent on the severity of depressive symptoms in women with type 2 diabetes. The severity of depressive symptoms in the group of non-diabetic women contributed to the severity of sleep disorders, vertigo, and a lack of energy. Conclusions: Climacteric symptoms significantly affect biopsychosocial status of perimenopausal women, irrespective of whether they have type 2 diabetes.