Vitamin D is a liposoluble secosteroid essential for the maintenance of the body's mineral balance. 1 Vitamin D participates in the enamel and dentin calcification 2-7 and the correct immune response to oral microbial infections. 2-7 Vitamin D acts by binding an intra-cellular receptor, the vitamin D receptor (VDR). 8 VDR is a nuclear transcription

Introduction: Oral pigmentary lesions may have different clinical characteristics, ranging from physiological pigmentation, such as melanin spots, to something more serious, such as malignant melanoma. Due to the great variety of pigmented lesions, the treatments are varied and individualized. Objective: This clinical case reports a case of melanocytic removal through a surgical technique that associates rotary instruments and scalpel blade. Case report: A 45-year-old patient, melanoderma, sought care at the Positivo University, complaining about the dark spots visible on his gum, and the discomfort they caused him when smiling. After the clinical examination, the presence of melanocytic pigmentation was diagnosed and the proposed treatment was surgical removal of spots with a drill and scalpel blade. In the immediate postoperative period, the patient presented good healing and reported only mild burning in the first three days. After 60 days, the gingiva was healed, with no relapsing spots. Conclusion: The technique chosen was effective because it presented adequate healing and absence of relapse of the pigmentation in the postoperative follow-up

Desquamative gingivitis is an oral sign of systemic changes that may be symptomatic or asymptomatic. It is generally related to immunological changes. This report is aimed at describing the case of a 51-year-old female patient, who presented with clinical desquamative gingivitis and was initially diagnosed and treated as necrotizing periodontal disease, but no improvement. The cause was hypothesized to be an autoimmune disease. Drug therapy was initiated as a combination of prednisone and topical clobetasol propionate 0.5% cream twice a day. After this treatment, there was an improvement in pain and the blistering of the gingiva. However, the gingiva remained erythematous. A biopsy led to the diagnosis of benign mucous membrane pemphigoid (BMMP). The BMMP case reported in this article has been successfully treated with systemic and topical immunosuppressive therapy. The efficacy of systemic corticosteroids with dapsone and multidisciplinary follow-up has been highlighted and can lead to the stabilization and adequate control of the disease.

As lesões pigmentadas na cavidade bucal têm diversas características clínicas, que podem variar desde uma pigmentação fisiológica, como as manchas melânicas, até algo mais grave, como o melanoma maligno. Pela grande diversidade de lesões pigmentadas, os tratamentos são variados e individualizados. Objetivo: Remover manchas melânicas por meio de uma técnica cirúrgica que associa instrumentos rotatórios e lâmina de bisturi. Relato de caso: Paciente de 34 anos, melanoderma, procurou atendimento na Universidade Positivo queixando-se das manchas escurecidas visíveis em sua gengiva e do incômodo que elas lhe causavam por se destacarem ao sorrir. Após o exame clínico, diagnosticou-se presença de pigmentações melânicas. O tratamento proposto foi a remoção cirúrgica das manchas com broca e lâmina de bisturi. No pós-cirúrgico imediato a paciente apresentou boa cicatrização e relatou apenas leve ardência nos três primeiros dias. Após 60 dias, a gengiva se apresentava cicatrizada, sem recidiva das manchas. Conclusão: A técnica escolhida mostrou-se efetiva pois houve cicatrização adequada sem recidiva da pigmentação no acompanhamento pós-operatório.