Despite the difficult time, the pandemic allowed teachers to work on biology curriculum contents. The aim of this study was to present discussions about the main difficulties faced by teachers and students in relation to remote classes in the teaching of biology in the pandemic scenario. The work is an integrative literature review, carried out through the electronic bases of publications: Google Academic, Scientific Electronic Library Online (SciELO) and the Periodic Portal CAPES. Through the keywords: COVID-19; Biology Teaching; Emergency remote education; Digital technologies. The choice of articles was 2