No abstract

A prospective double-blind trial was conducted in C rohn's disease subjects in whom a resection was being performed, to assess the hypothesis that marginal d isease would adversely influence healing of the anastomosis. Of 106 eligible patients. 51 completed a protocol of pathological assessment of the su rgical specimen and a water soluble contrast enema 10 to 15 days after the surgical procedure. Six were fo und to have radiological leaks and three add itional subjects had clinical leaks from the anastomosis. The proportion of leaks, both cUnical and radiological, was nine of 54. There was no trend to increasing rate of anastomotic breakdown with increasing marginal disease. Can J Gastroenterol 1989;3(3):95-97