Breast Cancer is the commonest maligrancy in woment. A study was carried out in the Department of Biochemistry, Dhaka Medical College to investigate some of the biochemical features that are associated with breast cancer occurring in Bangladeshi women. Thirty diagnosed breast cancer patients and thirty healthy women were selected. A questionnaire was used for collecting information regarding age, family history, physical activity and exercise, BMI, diet, smoking, alcohol abuse, addiction, details of menstrual and obstetric history, breast-feeding, parity, use of contraceptives and HRT. Blood samples were collected and tested for fasting lipid profiles, serum estrogen and progesterone. The study has revealed that high levels of serum total cholesterol (P<0.05), TAG (P<0.05), LDL-C (P<0.05) and low level of serum and HDL-C (P<0.05) were found to be associated with breast cancer. The study further reveals that blood levels of estrogen (P<0.05) and progesterone (P<0.05) were found to be lower than that of the controls. DOI: http://dx.doi.org/10.3329/bjmb.v6i2.17644 Bangladesh J Med Biochem 2013; 6(2): 58-62
This study was designed to compare the blood lipid profile and conventional cardiovascular risk factors in patients with acute coronary syndrome (ACS) and chronic stable angina (CSA). A total of 110 patients, 55 of which were of ACS and 55 with chronic stable angina (CSA) who underwent coronary angiography in the Department of Cardiology, BSMMU, Dhaka were enrolled for the study. Lipid profile and age, sex, diabetes mellitus, hypertension, hyperlipidemia, smoking habit, family history of premature coronary artery diseases (CAD) of the patients were recorded and compared. Mean±SD age of the studied patients was 52.2±10 years. Prevalence of diabetes mellitus (p<0.05) and hypertension (p <0.05) was significantly higher in patients with CSA than that with ACS. Frequency of hyperlipidemia, smoking habit and family history of CAD was similar between groups. Patients with CSA had significantly higher triple vessel diseases (TVD) (p < 0.001) and significantly lower high-density lipoprotein cholesterol (HDLc) (p < 0.05) compared to that of patients with ACS. ACS patients had significantly higher single vessel diseases (SVD) (p <0.001) compared to that of CSA but the distribution of low-density lipoprotein cholesterol (LDLc), total cholesterol and triglycerides were variable between groups. This study showed that CSA patients had substantially higher frequency of having some CVD risk factors with alteration in certain lipid profile parameters and higher number of triple vessels disease than patients with ACS. This might aid in selecting appropriate criteria for angiographic evaluation and better management of patients with coronary artery diseases. DOI: http://dx.doi.org/10.3329/bjmb.v7i2.22413 Bangladesh J Med Biochem 2014; 7(2): 52-56
CorrigendumThere is correction in the Journal of Dhaka Medical College, April 2009 issue (Vol. 18, No. 1). In the original article titled "Treatment of vitiligo with autologous epidermal transplantation using the roof of suction blisters, first in Bangladesh", the name of the first author will have to be read Khondoker MS instead of Khundkar SH, and in address of correspondence Dr. Md. Sajjad Khondoker instead of Prof. Shafquat Hussain Khundkar at page no. 58.On 15/02/2011, the first author's name was changed from SH Khundkar to MS Khondoker on the online edition of the journal on BanglaJOL.We report our experience of autologous epidermal transplantation for 30 (Thirty) patients with vitiligo. The vitiligo in 25 (Twenty five) patients was stable whereas in the rest (5) it was active. Autologous epidermal transplantation was performed using suction blister roofs from normal pigmented skin to vitiligo skin that was failed to repigment using topical steroid and/or psoralenultraviolet- A treatment. Grafts were well taken in all the patients. Only three of them are presented as case report in this article. There were no complications except mild hyper pigmentation at the donor areas. For the patient who had active vitiligo, depigmentation of the graft and concomitant Koebner‘s phenomenon at the donor site were observed 3 weeks after the procedure. We conclude that autologous epidermal transplantation using the roof of suction blisters is an excellent and safe regimenting procedure for stable, localized vitiligo and the active disease precludes transplantation. Key words: Epidermis surgery; vitiligo therapy; transplantation alutologous. DOI: 10.3329/jdmc.v18i1.6308 J Dhaka Med Coll. 2009; 18(1) : 58-63
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